Factor VIII concentrate: how to take it safely
Advate, Kogenate, Octanate
Reviewed by Pharm. Abeeb Junior
What it is for
Treats and prevents bleeding in people with haemophilia A.
How to take it
- Prescription medicine: take it exactly as your doctor or pharmacist told you.
- It is given by injection into a vein by a nurse or doctor, or by you or a carer once trained. Mix as taught.
- Store it as the pack says and keep a record of each dose.
When to take it
Given at the first sign of bleeding, or on a regular schedule to prevent bleeding, as your haemophilia team plans.
Take it with
Not applicable.
What to avoid
- Missing doses. Do not delay treatment of bleeding, especially in the head, neck, chest or belly.
- Aspirin and anti-inflammatory painkillers unless your doctor approves.
- Injections into the muscle.
Possible side effects
Headache, fever, pain at the injection site, mild rash.
Get help if
A bleed that does not stop with treatment, a head injury or severe headache, a rash with trouble breathing: get urgent help.
This is general information, not personal medical advice. Always follow your doctor's or pharmacist's instructions and read the leaflet that comes with your medicine. Medicines and doses can differ between products and people.