Methotrexate tablets: how to take it safely
Methotrexate, Trexall
Reviewed by Pharm. Abeeb Junior
What it is for
Treats rheumatoid arthritis, psoriasis and some other conditions, in low weekly doses.
How to take it
- Prescription medicine: take it exactly as your doctor or pharmacist told you.
- Swallow with water.
- Take it once a WEEK only, on the same day each week. Taking it daily can be fatal.
- Take folic acid as your doctor told you.
- You will need regular blood tests.
When to take it
Once a week, on the same day. Mark that day on your calendar.
Take it with
With or without food.
What to avoid
- Taking it every day by mistake.
- Alcohol.
- Pregnancy. Avoid pregnancy during treatment and for months after, for both women and men.
- Trimethoprim and co-trimoxazole.
- Anti-inflammatory painkillers unless your doctor approves.
- Live vaccines.
Possible side effects
Nausea, mouth ulcers, tiredness, hair thinning.
Get help if
Sore throat, fever, mouth sores, cough or breathlessness, unusual bruising, or yellow skin or eyes: get urgent help.
This is general information, not personal medical advice. Always follow your doctor's or pharmacist's instructions and read the leaflet that comes with your medicine. Medicines and doses can differ between products and people.