Prothrombin complex concentrate: how to take it safely
Beriplex, Octaplex, Kcentra
Reviewed by Pharm. Abeeb Junior
What it is for
Quickly reverses warfarin and treats serious bleeding from clotting factor deficiency.
How to take it
It is given by drip or injection into a vein by a doctor or nurse.
When to take it
Given once in an emergency, with vitamin K, as your doctor decides.
Take it with
Not applicable.
What to avoid
Tell your team if you have had a blood clot, a stroke or a heart attack, or an allergy to heparin.
Possible side effects
Headache, nausea, fever, low blood pressure, blood clots.
Get help if
Chest pain, a swollen painful leg, sudden weakness, trouble breathing or a rash: tell the staff straight away.
This is general information, not personal medical advice. Always follow your doctor's or pharmacist's instructions and read the leaflet that comes with your medicine. Medicines and doses can differ between products and people.